India, which won all three one-day games and the first T20, couldn't chase down Zimbabwe's 145-7 in the final game of the tour at Harare Sports Club.The under-strength Indian team, which is touring without a string of top stars, finished on 135-9, with Robin Uthappa top scoring with 42.
Legspinner Graeme Cremer took 3-18 for Zimbabwe, the best bowling performance of the game.
Earlier, opening batsman Chamu Chibhabha maintained his run of form with 67 from 51 balls with nine fours to hold together Zimbabwe's innings.
Bhuvneshwar Kumar and Mohit Sharma had two wickets each for India.
Zimbabwe upsets India by 2 runs in 1st T20